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The CPCRA Network
The CPCRA was formed in 1989 as a clinical
trials program that conducts research in primary care settings through a national network
of community-based clinical units. The CPCRA {currently} includes
16 units in 15 U.S. cities with more than 130 collaborating sites (in Bronx, NY; Camden, NJ; Chicago, IL; Denver, CO; Detroit, MI; Houston, TX; Newark, NJ; New Haven, CT; New Orleans, LA; New York, NY; Philadelphia, PA; Portland, OR; Richmond, VA; San Francisco, CA; and Washington, DC) that provide
HIV primary care for approximately 60,000 patients. Additionally, Associate Sites collaborate with the CPCRA network to enroll participants in targeted studies. In the SMART Study, four Regional Coordinating Centers oversee 27 U.S. associate sites (Arizona, California, Florida, Georgia, Illinois, Kansas, Minnesota, New Jersey, New York, North Carolina, Oklahoma, Texas, Wisconsin) and 187 sites in 33 countries (Argentina, Australia, Austria, Belgium, Brazil, Canada, Chile, Denmark, Estonia, Finland, France, Germany, Greece, Ireland, Israel, Italy, Japan, Lithuania, Luxembourg, Morocco, Netherlands, New Zealand, Norway, Peru, Poland, Portugal, Russia, South Africa, Spain, Switzerland, Thailand, Uruguay, United Kingdom).
Together, the collaborating sites have
enrolled more than 35,000 HIV-infected individuals in 47 clinical trials.
Participating sites include private physicians' practices, public
hospital clinics, freestanding community clinics, university and
veterans' hospital clinics, and drug-treatment facilities.
CPCRA Leadership and Structure
The components of the CPCRA include
the Network Principal Investigator, the Executive Coordinator, the
Management Group, the Steering Committee, the Standing Committees,
the Community Constituency Group, the Operations Center, and the
Statistical and Data Management Center (SDMC).
- The Network Principal Investigator
(PI) of the CPCRA is the chair of the Steering Committee and
has overall responsibility for the performance of the group.
- The Executive Coordinator of
the CPCRA directly assists the Network PI in coordinating the
activities of the Steering Committee and all of its standing committees.
- The Management Group represents
the operational services of the CPCRA. They assist the group leader
with implementation and continual oversight of all of the activities
of the group.
- The Steering Committee serves
as the principal governing body of the CPCRA and, as such, has
broad authority over resource allocation, direction and implementation
of the group’s scientific agenda, and overall policy development.
The standing committees report to the Steering Committee, and
their chairs are members of the Steering Committee.
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